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Ingredient guide

Urolithin A: evidence, dose and safety

Urolithin A is made by some gut bacteria from ellagitannins in pomegranates, berries and walnuts; many people make little of it. It is not authorised as a novel food in the EU, so we sell it only in the US.

At a glance

Strongest evidence
D Weak
Adult upper limit
1000 mg a day from food and supplements together
Safety checks
1 situation and 0 medicine or supplement interactions, checked against your answers in every plan
Reviewed
Atrum Labs clinical team (MD, PhD), November 2026

What the research looked at

Each line is one body of research, graded A (strong) to D (weak). How we grade evidence. What each study measured is explained in your personal plan.

GradeWho was studiedReferences
D Adults 40-90
  • Liu S et al. JAMA Netw Open 2022;5:e2144279 (PMID 35050355)
  • Singh A et al. Cell Rep Med 2022;3:100633 (PMID 35584623)

How much

  • Adult upper limit: 1000 mg a day from food and supplements together. Source: Highest dose in 4-month trials (Liu S et al. JAMA Netw Open 2022); US FDA GRAS notice GRN 791.
  • Children's doses are set by age, and some ingredients are for adults only.

Who should not take it, or should check first

  • Not suitable. No safety data in pregnancy or breastfeeding; trials enrolled adults 40-90.

Where we sell it

  • Not sold in Sweden.

Written and reviewed by the Atrum Labs clinical team (physician-scientists, MD, PhD) from our clinical knowledge base, version 0.2.0-draft. This page is general information, not medical advice. Food supplements are not a substitute for a varied, balanced diet and a healthy lifestyle.

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