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Ingredient guide
Rhodiola rosea extract: evidence, dose and safety
Rhodiola rosea is a plant from cold regions of Europe and Asia whose root extract is standardised to rosavins and salidroside.
At a glance
- Strongest evidence
- C Limited
- Dose in our plans
- 400 mg a day for adults
- Adult upper limit
- 680 mg a day from food and supplements together
- Safety checks
- 2 situations and 1 medicine or supplement interaction, checked against your answers in every plan
- Reviewed
- Atrum Labs clinical team (MD, PhD), November 2026
What the research looked at
Each line is one body of research, graded A (strong) to D (weak). How we grade evidence. What each study measured is explained in your personal plan.
| Grade | Who was studied | References |
|---|---|---|
| C | Fatigued adults |
|
How much
- Our plans usually use 400 mg a day for adults. The exact dose depends on your lab results, age and medicines.
- Adult upper limit: 680 mg a day from food and supplements together. Source: Trials used 144-680 mg a day (Ishaque S et al. BMC Complement Altern Med 2012).
- Children's doses are set by age, and some ingredients are for adults only.
Who should not take it, or should check first
- Not suitable. Insufficient safety data in pregnancy or lactation.
- A clinician checks first. Stimulating adaptogen; possible mood destabilisation.
Medicines and other supplements
- A clinician checks first. Possible MAO inhibition and additive effects with antidepressants.
Your plan is checked against every medicine you tell us about. If you take a medicine, ask your pharmacist or doctor before starting a new supplement.
Written and reviewed by the Atrum Labs clinical team (physician-scientists, MD, PhD) from our clinical knowledge base, version 0.2.0-draft. This page is general information, not medical advice. Food supplements are not a substitute for a varied, balanced diet and a healthy lifestyle.
See if it belongs in your plan