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Ingredient guide

Creatine monohydrate: evidence, dose and safety

Creatine is made in the body from amino acids and stored in muscle, with some coming from meat and fish. We use creatine monohydrate, the most studied form.

At a glance

Strongest evidence
A Strong
Dose in our plans
3 g a day for adults
Adult upper limit
5 g a day from food and supplements together
Safety checks
1 situation and 0 medicine or supplement interactions, checked against your answers in every plan
Reviewed
Atrum Labs clinical team (MD, PhD), November 2026

Authorised EU health claim

Creatine increases physical performance in successive bursts of short-term, high intensity exercise (beneficial effect with a daily intake of 3 g).

What the research looked at

Each line is one body of research, graded A (strong) to D (weak). How we grade evidence. What each study measured is explained in your personal plan.

GradeWho was studiedReferences
A Training adults
  • Kreider RB et al. J Int Soc Sports Nutr 2017 (ISSN position stand)
B Adults 50+
  • Chilibeck PD et al. Open Access J Sports Med 2017;8:213-26 (meta-analysis; PMID 29138605)
C Healthy older adults
  • Prokopidis K et al. Nutr Rev 2023;81:416-27 (meta-analysis; PMID 35984306)

How much

  • Our plans usually use 3 g a day for adults. The exact dose depends on your lab results, age and medicines.
  • Adult upper limit: 5 g a day from food and supplements together. Source: Maintenance dose 3-5 g a day (Kreider RB et al. J Int Soc Sports Nutr 2017).
  • Children's doses are set by age, and some ingredients are for adults only.

Who should not take it, or should check first

  • Not suitable. Not studied in kidney disease, and creatine raises blood creatinine, which hides real changes in kidney function.

Products with Creatine monohydrate

Written and reviewed by the Atrum Labs clinical team (physician-scientists, MD, PhD) from our clinical knowledge base, version 0.2.0-draft. This page is general information, not medical advice. Food supplements are not a substitute for a varied, balanced diet and a healthy lifestyle.

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